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Our top choices for Santa Ana hotels

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 2.2 mi from Santa Ana
9.0 out of 10, Wonderful, (5,972 reviews)
"Beautiful hotel, breakfast was wonderful, location was very convenient."
United States
Sandrelly
$138 nightly
The price is $151
Sep 28 - Sep 29
Total with taxes and fees
Hotel Riu Plaza Panama

2. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
4.9 mi from Santa Ana
7.8 out of 10, Good, (1,086 reviews)
"We had a wonderful stay at the resort, very relaxing and friendly atmosphere. Definitely recommending for family getaway."
United States
Joanna
$278 nightly
The price is $278
Oct 1 - Oct 2
Total with taxes and fees
Dreams Playa Bonita Panama - All Inclusive

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 2.2 mi from Santa Ana
8.6 out of 10, Excellent, (1,742 reviews)
"It was a beautiful stay ..enjoyed every moment"
United States
Devika
$133 nightly
The price is $133
Oct 14 - Oct 15
Total with taxes and fees
Megapolis Hotel Panamá

4. W Panama

W Panama
5.0 star property
Campo Alegre, 2 mi from Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"Wonderful staff!"
United States
Nikkia
$223 nightly
The price is $246
Oct 11 - Oct 12
Total with taxes and fees
W Panama

5. JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 2.7 mi from Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
"Great experience in great hotel You can’t be wrong if you book room with them, I will be back again for sure"
United States
Nemanja
$263 nightly
The price is $290
Oct 10 - Oct 11
Total with taxes and fees
JW Marriott Panama

6. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
1.3 mi from Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Great place to stay with the family."
United States
Richard
$169 nightly
The price is $186
Oct 10 - Oct 11
Total with taxes and fees
Marriott Panama Hotel

7. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 2.4 mi from Santa Ana
9.0 out of 10, Wonderful, (2,067 reviews)
"Good area around for short time visit"
United States
Eliel
$59 nightly
The price is $65
Sep 22 - Sep 23
Total with taxes and fees
Principe Hotel and Suites

8. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.5 mi from Santa Ana
9.0 out of 10, Wonderful, (1,007 reviews)
"Great location and nice hotel."
United States
Olga
$183 nightly
The price is $202
Oct 21 - Oct 22
Total with taxes and fees
Central Hotel Panama Casco Viejo

9. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 0.7 mi from Santa Ana
9.8 out of 10, Exceptional, (750 reviews)
"Amazing service and beautiful hotel"
United States
Jose
$356 nightly
The price is $391
Oct 6 - Oct 7
Total with taxes and fees
Sofitel Legend Casco Viejo, Panama City

10. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 1.4 mi from Santa Ana
8.6 out of 10, Excellent, (1,002 reviews)
"It was a nice getaway if you didn't want to be directly in the city"
United Kingdom
Samantha
$93 nightly
The price is $102
Oct 2 - Oct 3
Total with taxes and fees
Radisson Hotel Panama Canal

11. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 2 mi from Santa Ana
9.2 out of 10, Wonderful, (1,261 reviews)
"great location, great hotel"
United States
Sandra
$89 nightly
The price is $98
Oct 7 - Oct 8
Total with taxes and fees
The Executive Hotel

12. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 2.2 mi from Santa Ana
9.0 out of 10, Wonderful, (1,159 reviews)
"Great breakfast options, Clean rooms, helpful staff"
United States
Abeke
$111 nightly
The price is $123
Sep 27 - Sep 28
Total with taxes and fees
Waymore Hotel Spa & Casino

13. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 2.1 mi from Santa Ana
9.6 out of 10, Exceptional, (456 reviews)
"One of the best hotel in Panama🔥"
United States
Abraham
$187 nightly
The price is $206
Oct 3 - Oct 4
Total with taxes and fees
Hyatt Regency Panama City

14. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
El Cangrejo, 2.4 mi from Santa Ana
8.8 out of 10, Excellent, (1,035 reviews)
"It was an amazing place and center located to all restaurants and night life"
United States
Abraham
$77 nightly
The price is $87
Oct 21 - Oct 22
Total with taxes and fees
Riande Urban Hotel

15. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 2.1 mi from Santa Ana
9.4 out of 10, Exceptional, (2,229 reviews)
"Great hotel, great location"
Canada
Catherine
$103 nightly
The price is $114
Oct 10 - Oct 11
Total with taxes and fees
Plaza Paitilla Inn Hotel

16. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista, 1.9 mi from Santa Ana
9.0 out of 10, Wonderful, (1,004 reviews)
"Amazing stay"
United States
Kevin
$245 nightly
The price is $270
Oct 9 - Oct 10
Total with taxes and fees
Hilton Panama

17. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco, 3.5 mi from Santa Ana
8.8 out of 10, Excellent, (1,003 reviews)
"It was a great stay"
United States
Shaniyah
$132 nightly
The price is $146
Oct 2 - Oct 3
Total with taxes and fees
Aloft by Marriott Panama

18. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 3.2 mi from Santa Ana
9.6 out of 10, Exceptional, (1,346 reviews)
"excellent breakfast great location"
United States
Maria
$98 nightly
The price is $108
Oct 3 - Oct 4
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica

19. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
4.7 mi from Santa Ana
8.2 out of 10, Very good, (1,000 reviews)
"Great place, well maintained, greate restaurants, staff very respectful."
Canada
Flavio
$206 nightly
The price is $227
Oct 2 - Oct 3
Total with taxes and fees
The Westin Playa Bonita Panama

20. Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Campo Alegre, 1.8 mi from Santa Ana
8.8 out of 10, Excellent, (764 reviews)
"Great hotel, good breakfast friendly staff"
United States
Kitania
$107 nightly
The price is $118
Sep 23 - Sep 24
Total with taxes and fees
Marriott Executive Apartments Panama City, Finisterre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Casco View Life Residences
4.0 star property
9.0
Wonderful
106 reviews
View
Interior
Hotel Caracas - Casco Viejo
3.0 star property
8.0
Very good
16 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.8
197 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
13 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Santa Ana
Learn more about Santa Ana

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Historic Attractions: Visit iconic sites like Old Santa Ana Square, Panama Viejo, and the Panama Canal to delve into the city's rich history.
  • Vibrant Neighborhood: Experience the lively atmosphere of Santa Ana with friendly locals and a family-friendly vibe.
  • Cultural Experiences: Explore the Iglesia Santa Ana and local history museums that showcase Panamanian heritage.
  • Outdoor Activities: Enjoy the surrounding hills and beautiful parks, perfect for relaxation and recreation.
  • Diverse Accommodations: Choose from a variety of hotels and vacation homes to suit both business and leisure travelers.

Find great hotels near Santa Ana

Explore a variety of hotel accommodations in Santa Ana, Panama City, ideal for both business travelers and vacationers. From pet-friendly options to city-themed hotels, you'll find the perfect stay to suit your needs. Consider Villa Ana for a unique experience or choose from various vacation homes to enhance your trip in Panama. Enjoy all the comforts of home while immersing yourself in the vibrant local culture.

  • Central Hotel Panama Casco Viejo: Nestled in the heart of the historic district, Central Hotel Panama Casco Viejo is a charming 4-star hotel with a guest rating of 9.0. Ideal for couples seeking a romantic getaway, this hotel offers unique romance packages, ensuring a memorable experience. Guests can indulge in luxurious amenities, including a full-service spa and an outdoor pool, perfect for relaxation. With 24-hour room service and a dedicated Champagne service, every moment can be a special occasion. Enjoy soothing spa treatments, including massages and steam room access, all designed to enhance your romantic retreat.
  • American Trade Hotel: A vibrant 4.5-star destination with a guest rating of 9.4, American Trade Hotel is perfect for families and adventure seekers. Located just 0.4 miles from Santa Ana, this hotel seamlessly combines comfort and excitement. Enjoy a range of adventure sports and recreation activities nearby, from hiking to bike rentals. The hotel also caters to families with child-friendly amenities and features picturesque garden views from the restaurant. Romance packages and in-room massages add a touch of luxury, while the outdoor pool provides a relaxing oasis after a day of exploration.
  • Sofitel Legend Casco Viejo, Panama City: This opulent 5-star hotel boasts a remarkable guest rating of 9.8 and is situated 0.7 miles from Santa Ana. Sofitel Legend offers a luxurious spa experience paired with exceptional business travel facilities. Guests can unwind by the outdoor pool, enjoy refreshing drinks at the poolside bar, and indulge in facial treatments or outdoor massages. With its stunning historical surroundings and high-end amenities, this hotel is an ideal choice for those seeking a lavish vacation in Panama City.

Where to stay near Santa Ana

Discover the vibrant charm of Santa Ana, a lively neighborhood in Panama City, where friendly locals and a family-friendly atmosphere await. Explore the nearby districts, enjoying a mix of business and leisure vibes. Don’t miss the chance to experience the local culture, savor delicious cuisine, and relax in beautiful parks. With its blend of luxury and relaxation, Santa Ana is the perfect base for your Panamanian adventure, making it an unforgettable destination in Panamá Province.

  • Panama City: As the vibrant heart of Panama, Panama City offers a unique blend of modernity and history. Nestled along the Pacific coast, the city is a bustling hub for business and tourism alike. Visitors can enjoy a variety of experiences, from exploring the iconic Panama Canal to shopping in its many malls and markets. The scenic waterfront, parks, and local beaches provide ample opportunities for relaxation and outdoor activities. The city experiences a steady flow of tourists year-round, with peak seasons in January, July, and September, making it an ideal destination for families and business travelers.
  • Casco Viejo: A UNESCO World Heritage site, Casco Viejo is a charming neighborhood located 0.4 miles from Santa Ana. This historic district is renowned for its colonial architecture, vibrant street life, and rich cultural scene. Visitors can wander through its cobblestone streets, visit art galleries, and savor local cuisine in quaint eateries. The area enjoys a consistent influx of tourists, particularly in January and during the spring months, making it a lively spot for family and business gatherings. Casco Viejo is also close to stunning beaches and parks, making it a delightful blend of leisure and cultural exploration.
  • San Felipe: Also situated 0.4 miles from Santa Ana, San Felipe is another historic neighborhood that showcases Panama's rich heritage. With its colorful buildings and lively atmosphere, it attracts visitors year-round, especially during the peak months from December to February. Travelers can indulge in shopping at local markets, relax at nearby parks, or enjoy the beautiful beach scenery. San Felipe offers a wonderful mix of family-friendly activities and cultural experiences, making it a must-visit area for anyone looking to immerse themselves in Panamanian history and lifestyle.

Things to do in Santa Ana

Santa Ana in Panama City is perfect for families and business travelers alike, offering a vibrant mix of activities. You can explore shopping areas and malls, unwind at local resorts, or take guided walking tours to discover the attractions. Don't miss out on recreational activities that showcase the city's culture and charm, making your visit both enjoyable and memorable.

Shopping

In Santa Ana, visit the Albrook Mall, one of the largest shopping centers in Panama, featuring a wide range of stores from international brands to local boutiques. For a more traditional experience, explore the Mercado de Santa Ana, where you can find unique souvenirs and handcrafted items.

Recreation

In Santa Ana, the Zen Garden offers holistic wellness treatments amidst lush greenery, promoting relaxation and rejuvenation. Enjoy yoga classes on serene outdoor decks while indulging in organic spa therapies that harness local ingredients for a refreshing and revitalizing experience.

Adventure

Explore the scenic Santa Ana Park, where you can hike lush trails and enjoy birdwatching. For a thrilling experience, try zip-lining through the treetops, taking in panoramic views of the vibrant landscape. Don't miss the chance to taste local street food at nearby vendors.

Nightlife

In Santa Ana, Panama City, the vibrant nightlife features venues like La Tana, known for its lively atmosphere and local music, and Casa Jaguar, which offers delicious cocktails and a laid-back vibe. Enjoy dancing and mingling with locals in this energetic neighborhood.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your choices based on your budget, desired location, and preferred type of accommodation. To find the best prices and discounts, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by booking an Expedia package that combines your Santa Ana hotel with your flights and activities.

Find the best attractions near Santa Ana

Santa Ana, Panama, is perfect for family vacations and city-themed getaways. Visitors can explore popular attractions like Old Santa Ana Square, Panama Viejo, and the Panama Canal. Culture enthusiasts will appreciate the Iglesia Santa Ana and the local history museum, while outdoor lovers can enjoy the surrounding hills. With a mix of history and vibrant city life, Santa Ana offers a diverse experience for all types of travelers.

  • Metropolitan Cathedral of Panama: This stunning cathedral, located half a mile from Santa Ana, showcases a beautiful blend of Spanish colonial architecture and local culture. Its intricate design and historical significance make it a must-visit for anyone interested in Panama's rich heritage.
  • Interoceanic Canal Museum: Also located half a mile away, this museum offers an engaging journey through the history of the Panama Canal. Interactive exhibits and artifacts provide insights into the canal's construction and its impact on global trade and travel.
  • Flag of Cerro Ancón: A short 0.6-mile hike leads you to this scenic hill, where you can enjoy breathtaking views of Panama City and the surrounding landscape. It's a perfect spot for outdoor enthusiasts and photography lovers alike.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnySlightly HighSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageAverage
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighSlightly High

The nearest major airports for your trip to Santa Ana

For your visit to Santa Ana, Panama, you can fly into two major airports. Panama City (PTY-Tocumen Intl.) is situated 13 miles away, with nearby luxury hotels such as The Santa Maria, JW Marriott Panama, and Hilton Panama offering various transportation options to the airport. Alternatively, Panama City (PAC-Marcos A. Gelabert Intl.) is just 2 miles from Santa Ana, featuring nearby hotels like W Panama and Sofitel Legend Casco Viejo, both providing convenient shuttle services. For a more distant option, Rio Hato (RIH-Scarlett Martinez Intl.) is located 57 miles away, with hotels like The Buenaventura Golf & Beach Resort offering shuttle services as well.

Frequently asked questions

What other neighbourhoods are similar to Santa Ana?
The best areas to stay that are similar to Santa Ana for a rich cultural experience are Casco Viejo and parts of El Chorrillo.

Casco Viejo, also known as the Old Quarter, is a UNESCO World Heritage site and is a short walk from Santa Ana. This area is characterized by its beautifully restored historic architecture, narrow cobblestone streets, and historic plazas like Plaza de la Independencia and Plaza Bolívar. It's a prime location for those interested in history, architecture, and a lively evening atmosphere with many restaurants and rooftop bars. Couples often enjoy the romantic setting and the variety of dining options.

El Chorrillo, directly adjacent to Santa Ana, offers a more local and authentic look into daily Panamanian life. While it lacks the tourist infrastructure of Casco Viejo, it provides a genuine experience of the city's local culture, with traditional eateries and community spaces.
What are the best hotels in Santa Ana that travelers recommend?
For a highly recommended hotel in Santa Ana, consider Hostal La Cigarra.

Hostal La Cigarra, with a review rating of 7.6, is praised by guests for its convenient location and comfortable rooms. This property features a traditional design and is situated within a historical district, making it ideal for those interested in exploring the area's heritage. It's also very close to the Mola Museum, just 0.3 miles away, and the Museum of History Panama, located 0.4 miles from the hostal. Additionally, the property is near a shopping district and outlets, offering easy access to retail therapy.
What are the top pet-friendly hotels in Santa Ana?
For a top pet-friendly hotel in Santa Ana, consider Hostal La Cigarra.

Hostal La Cigarra, with a 7.6 rating, is a traditional property that permits pets, although a cleaning fee may apply. This hotel is conveniently located in a historical district, with the Museum of History Panama just 0.4 miles away and the Mola Museum only 0.3 miles away, making it easy to explore local attractions. Guests often praise its convenient location and comfortable rooms.
What are the best budget hotels in Santa Ana?
For budget-friendly accommodations in Santa Ana, Hostal La Cigarra and Hotel República are both excellent choices.

Hostal La Cigarra, with a review rating of 7.6, offers comfortable rooms and free WiFi. Its location is particularly convenient, placing you within easy reach of the Amador Theater, the Museum of History Panama, and the Metropolitan Cathedral of Panama, all under half a mile away. The hostal also has a traditional design and is situated within a historical and shopping district, with outlets nearby.

Another great option is Hotel República, which provides free WiFi and features a lovely rooftop terrace. This hotel also boasts a traditional design and is located in a historical district. From here, you are less than a mile from the Amador Theater, the National Bank House Museum, the Museum of History Panama, and the Metropolitan Cathedral of Panama.
When is the best time to go to Santa Ana?
The best time to go to Santa Ana, Panamá Province, Panama, is during the dry season, which runs from mid-December to mid-April. This period offers pleasant weather conditions for exploring the city and its surroundings.

During the dry season, you can expect sunny days and lower humidity, making it ideal for walking tours of the historic Casco Viejo district or visiting the Panama Canal. The temperatures are consistently warm, typically in the high 80s Fahrenheit (around 30-32°C), but with a refreshing breeze. This time of year is especially good for couples looking to enjoy outdoor dining and evening strolls without the interruption of rain.

For travelers who prefer fewer crowds and don't mind occasional rain showers, the shoulder seasons, particularly May and November, can also be a good option. During these months, you'll still experience warm temperatures and lush greenery, and hotels might offer slightly better value.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Ana.
How much is the nightly rate at a Santa Ana hotel?
Prices for hotels in Santa Ana often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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